Figure 1
From: Association of Polymorphisms in Pharmacogenetic Candidate Genes with Propofol Susceptibility

Clinical characteristics of patients during anesthesia induction. Anesthesia was induced with propofol via target-controlled-infusion (TCI) at 4 µg/ml. At OAA/S scores of 5, 4, 3, 2, 1, and 0, the effect-site concentration (Cep), bispectral index (BIS), onset time and total propofol were recorded. (A,B,C and D), left, reflect the Cep, BIS, onset time and total propofol recorded at OAA/S scores of 5, 4, 3, 2, 1, and 0. (A,B,C and D), right, reflect the distribution of Cep, BIS, onset time and total propofol at the score of 0, when patients lost consciousness. The different colors in Fig. 1, right side, obviously reflect the wide distribution of Cep, BIS, onset time and total propofol values at the score of 0, when patients lost consciousness. Variance between different groups was analyzed by one-way ANOVA. *P < 0.05 vs. Cep and BIS at an OAA/S score of 5 in (A and B); *P < 0.05 vs. onset time and total propofol at an OAA/S score of 4 in (C and D).