Figure 3

Differential PBMC gene expression between healthy controls vs breast cancer patients. Graphs (a–c) represent the mean relative log₁₀ transformed gene expression (±SEM) as quantified using quantitative real time qRT-PCR. The relative expression of the following genes is significantly downregulated in PBMCs isolated from breast cancer patients compared to healthy controls: (a) Log₁₀ NRP-1, (b) Log₁₀ SNAI1 and (c) Log₁₀ SEMA4A. Target gene expression levels are normalized against GUSB gene expression and scaled to expression levels in control cases. P < 0.05 considered to indicate statistical significance. ***p < 0.001, Independent samples T-test.