Figure 6
Age-dependent differential plasma proteins and PBMC expression profiles between breast cancer patients and healthy controls. Interaction plots of the estimated marginal means for soluble proteins (a) NRP-1, (b) PlGF, (c) VEGF and (d) TGFB-1; and estimated marginal means of relative log10 transformed gene expression in PBMCs of (e) NRP-1, (f) PlGF, (g) VEGF, (h) TGFβ-1, (i) PLXNA1, (j) VEGFR3, (k) SNAI1 and (l)SEMA4A compared between early onset breast cancer patients (18–35 years) (solid black line) and older patients (>35 years) (dashed black line) vs age-matched healthy controls.
