Figure 1 | Scientific Reports

Figure 1

From: Reconstruction of pathway modification induced by nicotinamide using multi-omic network analyses in triple negative breast cancer

Figure 1

Effects of nicotinamide on breast cancer cell lines. (a) MDA-MB-231 cells were treated with 15, 25 and 45 mM nicotinamide. Dose-dependent cytotoxic effects were assessed every 24 and 48 h using a WST-1 assay. The data represent the mean ± SD (**P < 0.01). The cell morphology of MDA-MB-231 cells treated with 25 mM nicotinamide for 48 h via (b) light microscopy (left, original magnification x 100) and H&E staining (right, original magnification x 100). (c) Colony formation assays of MDA-MB-231 cells treated with nicotinamide 25 mM for 48 h. (d) The bar graph indicates colony numbers revealed by the colony formation assay. The data represent the mean ± SD (*P < 0.05).

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