Table 2 Results of the DNA methylation analysis.

From: Attention, cognitive control and motivation in ADHD: Linking event-related brain potentials and DNA methylation patterns in boys at early school age

Gene

CpG site

FBB-ADHS total score

dRTVar

Cue-P3

Nogo-P3

correlation

p-value

FDR

correlation

p-value

FDR

correlation

p-value

FDR

correlation

p-value

FDR

COMT − 29 CpGs

cg09926649

−0.424

0.0003

0.010

         

cg08289189

0.395

0.0014

0.020

      

−0.361

0.0037

0.036

cg16834011

         

−0.375

0.0018

0.034

cg07019740

   

0.250

0.0450

 

0.252

0.0429

 

0.371

0.0023

0.034

cg23268677

         

0.313

0.0105

0.076

ANKK1 − 10 CpGs

cg02682525

0.443

0.0002

0.002

         

cg16158779

0.403

0.0007

0.004

         

cg15946653

0.386

0.0012

0.004

      

−0.315

0.0095

0.095

cg20667575

0.382

0.0014

0.004

         

cg16405454

0.305

0.0122

0.024

         

TPH2 − 19 CpGs

cg14791008

0.426

0.0004

0.008

−0.364

0.0028

0.050

      

cg18701449

   

−0.337

0.0053

0.050

      

BDNF − 50 CpGs

cg11806762

−0.263

0.0317

       

0.408

0.0006

0.031

cg11241206

0.327

0.0068

          

cg25457956

         

−0.301

0.0135

 

NGFR − 24 CpGs

cg25226226

0.381

0.0015

0.027

         

cg17369032

0.367

0.0022

0.027

         

cg01438403

0.341

0.0048

0.035

   

−0.275

0.0241

    

cg04613258

0.333

0.0058

0.035

      

−0.304

0.0124

 

DPP10 − 45 CpGs

cg22670147

      

−0.390

0.0011

0.035

   

cg19651219

0.320

0.0083

    

−0.380

0.0015

0.035

   

cg24654266

      

−0.353

0.0034

0.051

   

cg21322022

      

−0.322

0.0080

0.090

   

cg00089091

         

0.309

0.0110

 

cg19211931

      

−0.307

0.0116

    
  1. Those genes fulfilling the combined statistical thresholds are presented. All probes linked to these genes with at least one correlation of medium effect are listed. Those CpGs fulfilling our statistical criteria (for details see text) are printed in bold. Only FDRs < 0.1 are listed. Abbreviations: FBB-ADHS (German ADHD rating scale); FDR = false discovery rate; dRTVar = difference of reaction time variability between blocks with and without motivational incentives.
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