Figure 2
From: Sequence variant at 4q25 near PITX2 associates with appendicitis
Locus plot for combined Icelandic and Dutch data showing the association of rs2129979 and surrounding variants at 4q25 with appendicitis (N = 8,566). The leading variant is shown as a purple circle, and other variants are coloured according to correlation (r2) with the leading marker (legend at top-right). −log10P values are shown along the left y-axis, and correspond to the variants depicted in the plot. The right y-axis shows calculated recombination rates at the chromosomal location, plotted as a solid red line. PITX2 is located 177 kb upstream of rs2129979.
