Table 2 Association of the appendicitis and previously reported atrial fibrillation signals at 4q25 with appendicitis (APP; N = 7,427) and atrial fibrillation (AF; N = 13,471) in Iceland. A chi-square test was used to compute P-values.
From: Sequence variant at 4q25 near PITX2 associates with appendicitis
Publication PMID | Marker | Position | Allele (min/maj) | MAF (%) | ORAF (95% CI) | PAF | ORAPP (95% CI) | PAPP | Distance (BP) | r2 with rs2129979 (IS) | D′ |
|---|---|---|---|---|---|---|---|---|---|---|---|
Current | rs2129979 | chr4:110799841 | G/T | 29.3 | 1.17 (1.13, 1.21) | 1.3 × 10−18 | 1.14 (1.09, 1.19) | 3.5 × 10−9 | NA | NA | NA |
17603472 | rs2200733 | chr4:110789013 | T/C | 11.8 | 1.49 (1.42, 1.56) | 3.0 × 10−60 | 1.07 (1.01, 1.14) | 0.03 | 10,828 | 0.32 | 1 |
17603472 | rs10033464 | chr4:110799605 | T/G | 8.32 | 1.23 (1.16, 1.30) | 2.0 × 10−12 | 0.99 (0.93, 1.05) | 0.74 | 236 | 0.04 | 1 |
26497660 | rs6843082 | chr4:110796911 | G/A | 20.1 | 1.43 (1.38, 1.49) | 1.6 × 10−73 | 1.04 (0.98, 1.30) | 0.16 | 2,930 | 0.11 | 0.42 |
26497660 | rs1448817 | chr4:110719897 | G/A | 24.8 | 1.25 (1.20, 1.30) | 1.3 × 10−32 | 1.09 (1.04, 1.14) | 2.0 × 10−4 | 79,944 | 0.38 | 0.69 |
