Figure 4

Live imaging of chromosomal domain formation during early embryogenesis. Imaging of FIB-1 (fibrillarin protein, nucleolus marker); HPL-2 (HP1 protein, heterochromatin marker); H4K20me1 mintbody (antibody fragment against mono-methylated lysine 20 of histone H4); and histone H2B. “m” indicates mitotic chromosomes or nucleus. Other signals are from interphase nuclei (arrows indicate representative nuclei). Bar, 5 μm.