Figure 1
From: Quantification of within-sample genetic heterogeneity from SNP-array data
Single-sample SNP array diversity measures. TCGA breast cancer sample TCGA-A2-A0D44 was used as an example, only segments with length >100 probes are analysed. Normalisation was performed so that both logR and mBAF values would range from 0 to 1. (a) Segmented logR and mirrored B allele frequency (mBAF) data. (b) 10-bin histogram of normalised logR values. (c) 2D plot of all segments. Circle are centred on the logR and mBAF values of each segment, their sizes are proportional to segment length. Colours indicate the total copy number of each segment, as reported by ASCAT.
