Figure 6

Imaging structural variability in bovine bone. Large-scale image of a transverse section of cortical bovine femur in THG (a) and SHG (b). This large-scale image includes an osteon with a well-defined radial organization (around the Haversian channel, red arrow), and a surrounding fibrolamellar region. Scale bar, 100 µm. (c) (resp. (d)), zoom into the rectangle area in (a) (resp. (b)). At the bottom and top parts of the images, lamellar regions surrounding vascular channels (white arrows in (a,b)) correspond to well-aligned lacunae and canaliculi, while the fibrous region in the center shows rounder lacunae and more disordered canaliculi. Scale bar, 10 µm.