Table 2 Prediction of Gram+ and Gram- secretory proteins from their mature domains.

From: MatureP: prediction of secreted proteins with exclusive information from their mature regions

Classifier

AUC (%)

Gram−

Gram+

Preprotein (#P1)

97.96

97.59

MatureP (#M22)

85.79

90.04

Disorder (#M7)

74.61

82.4055

  1. We measured the performance of the main classifiers (“preprotein” and “mature domain”) on a set of secretory proteins predicted in other bacterial proteomes. For this analysis we selected 25 Gram- and 10 Gram+ bacteria and collected 7120 and 1361 secretory proteins correspondingly (see Methods; Table S5). The E. coli K-12 secretome was excluded since it was used for the initial training.
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