Figure 3
From: Methylation of DACT2 promotes breast cancer development by activating Wnt signaling
The effects of DACT2 on breast cancer cell proliferation and cell cycle (A) The effects of DACT2 on cell proliferation were measured by the MTT assay for 120 hours. Each experiment was repeated three times. Vector: control group; DACT2: DACT2 re-expressed breast cancer cells; NC: negative control; siRNA: knockdown DACT2 breast cancer cells. **P < 0.01, ***P < 0.001. (B) The effects of DACT2 on colony formation in breast cancer cell lines. Each experiment was repeated three times. **P < 0.01 (C) Cell phase distribution in DACT2 unexpressed and re-expressed MDA-MB-468 and HBL100 cells, as well as cell phase distribution before and after knockdown of DACT2 in MDA-MB-231 cells. Each experiment was repeated three times. *P < 0.05, **P < 0.01, ***P < 0.001.
