Table 1 The association of DACT2 methylation status and clinical factors in human breast cancer patients.

From: Methylation of DACT2 promotes breast cancer development by activating Wnt signaling

  

Methylation status

 

Clinical parameter

Number (n = 153)

Unmethylated N = 77(50.3%)

Methylated N = 76(49.7%)

p value

Age

    

 <50

72

38

34

0.57

 ≥50

81

39

42

 

Tumor grade

    

 I–II

93

44

49

0.35

 III

60

33

27

 

Tumor stage

    

 1–2

121

63

58

0.40

 3–4

32

14

18

 

Tumor size

    

 <4 cm

114

63

51

0.037*

 ≥4 cm

39

14

25

 

Lymph node metastasis

    

 no

79

44

35

0.17

 yes

74

33

41

 

ER status

    

 Positive

30

15

15

0.97

 Negative

123

62

61

 

PR status

    

 Positive

48

23

25

0.69

 Negative

105

54

51

 

HER2 status

    

 Positive

131

68

63

0.57

 Negative

22

9

13

 
  1. * P values are obtained from χ 2 test, significant difference, *P < 0.05.
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