Figure 1 | Scientific Reports

Figure 1

From: C2238 ANP gene variant promotes increased platelet aggregation through the activation of Nox2 and the reduction of cAMP

Figure 1

C2238/αANP induces platelet activation. (A,B) Platelets were incubated without the peptide or with either T2238/αANP or C2238/αANP at the specified concentration (10−6 M or 10−10 M) and the platelet activation was triggered by a sub-threshold concentration of collagen (0.3 µg/ml). Platelet aggregation (A) and the concentration of the soluble CD40 ligand released by platelets (B) were assessed. N = 12. The results were expressed as mean ± SEM. In all the groups, a similar volume of solvent was added.

Back to article page