Figure 4

C2238 ANP gene variant is associated with increased platelet aggregation and oxidative stress. (A–D) Platelet aggregation (A), soluble CD40 ligand release (B), platelet hydrogen peroxide levels (C) and platelet Nox2 activity were assessed in subjects not carrying the variant and in subjects carrying the C2238 ANP gene variant. The results were expressed as mean ± SEM.