Figure 2 | Scientific Reports

Figure 2

From: The CCAAT-Binding Complex Controls Respiratory Gene Expression and Iron Homeostasis in Candida Glabrata

Figure 2

Transcriptome analyses of Hap5 impact on gene expression. The wild type and hap5Δ strains were grown in three different conditions (rich media, iron excess or iron starvation) and their transcriptomes were compared using microarrays. (A) Venn diagram representing the overlaps between the lists of Hap5 ChIP targets being significantly down regulated compared with wild type in YPD (blue line), BPS (green line) or iron excess (black line). The red line includes the only Hap5 ChIP target (GRX4) which was significantly up-regulated upon BPS treatment. The gene names are from the S. cerevisiae orthologs, when available. (B) Eisengram of the expression profiles of the genes from the Venn diagram. The values used are log2 of hap5Δ/wild type expression ratios. The color scale is indicated. The conditions used are 1: YPD; 2: iron excess (2 mM FeSO4 for 30 minutes); 3: iron starvation (0.5 mM BPS for 30 minutes).

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