Figure 6
From: Structural and Biochemical Characterization of Poly-ADP-ribose Polymerase from Trypanosoma brucei

TbPARP (A) and PAR (B) localization was detected with anti-TbPARP and anti-PAR polyclonal antibodies, respectively, in wild type bloodstream parasites. DAPI was used to identify nuclear and kinetoplastid DNA. Merge panels show that both TbPARP and PAR are localized to the nucleus upon hydrogen peroxide treatment. Bar: 5 µm.