Figure 2
From: Cycles of vascular plexus formation within the nephrogenic zone of the developing mouse kidney
The E11 and E11.5 kidneys are vascularised by blood vessels that carry erythroid cells and connect to the caudal and common iliac artery. (A–D) E11 kidney and the surrounding tissue. (B) Rendered image from A, showing the E11 metanephric mesenchyme, ureteric bud, and Wolffian duct. (C) Rendered image from A, showing the location of the major blood vessels in relation to the kidney. (D) Cartoon illustrating the region displayed in A-C (dashed white box) in relation to the caudal part of the mouse embryo (kidneys in yellow). (E-H) E11.5 kidney and the surrounding tissue. (F) Rendered E11.5 kidney, from E. (G) Rendered kidney and major blood vessels, from E. (H) Cartoon illustrating the region displayed in E-G (dashed white box) in relation to the caudal part of the mouse embryo (kidneys in yellow). (I–L) Erythroid cell carrying blood vessels form a ring around the ureteric bud at E11 and E11.5. Arrowhead in J shows the vascular ring carrying erythroid cells. (M) The E12.5 kidney is vascularised by blood vessels carrying erythroid cells (inset image in M shows that the erythroid cells in the E12.5 kidney are nucleated). UB, ureteric bud; WD, Wolffian duct; MM, metanephric mesenchyme; PWM, peri-Wolffian mesenchyme. Scale bars: 100 µm.
