Table 5 Predicted daily dosages based on PK-PD modelling.
From: Pharmacokinetic and pharmacodynamic modeling of cyadox against Clostridium perfringens in swine
Predicted daily doses | Target attainment rate | |
---|---|---|
50% | 90% | |
Bacteriostatic (E = 0) | 13.2 | 29.3 |
Bactericidal (E = −3) | 19.70 | 42.56 |
4log10 reduction in count (E = −4) | 25.46 | 54.50 |