Table 1 Clinical characteristics of subjects with and without SRC.

From: Hyperuricemia and overexcretion of uric acid increase the risk of simple renal cysts in type 2 diabetes

 

With SRC(n = 839)

Without SRC(n = 3786)

P-value

Age (years)

64.43 ± 10.40

59.65 ± 11.74

<0.001

Men (n, %)

579, 69.0%

2208, 58.3%

<0.001

BMI (kg/m2)

25.22 ± 3.55

25.02 ± 3.59

0.150

DD (years)

11.15 ± 7.22

10.35 ± 7.27

0.005

Albuminuria (n, %)

290, 35.8%

958, 26.2%

<0.001

SUA (µmol/L)

336.80 ± 97.37

320.79 ± 85.93

<0.001

SCr (µmol/L)

81.46 ± 52.54

70.37 ± 25.86

<0.001

eGFR (mL/min/1.73 m2)

93.60 ± 30.01

102.82 ± 28.26

<0.001

ALT (U/L)

17 (12–26)

19 (14–29)

<0.001

AST (U/L)

18 (15–23)

19 (15–24)

0.021

γ-GT (U/L)

24 (17–36)

25 (18–40)

0.016

TC (mmol/L)

4.56 ± 1.14

4.74 ± 1.17

<0.001

TG (mmol/L)

1.34 (0.91–1.89)

1.35 (0.94–2.01)

0.247

HDL-C (mmol/L)

1.06 ± 0.29

1.09 ± 0.30

0.017

LDL-C (mmol/L)

2.69 ± 0.91

2.83 ± 0.88

<0.001

FPG (mmol/L)

7.66 ± 2.51

7.93 ± 2.91

0.007

HbA1C (%)

8.68 ± 2.22

8.64 ± 2.05

0.604

24-h UUA (µmol)

3034.36 ± 1515.62

2980.05 ± 1314.67

0.396

24-h UCr (µmol)

10607.07 ± 5604.81

10377.53 ± 5378.55

0.373

24-h UGLU (mmol)

6.32 (0.59–40.18)

7.81 (0.51–42.82)

0.691

FEUA (%)

6.92 ± 2.73

6.64 ± 2.50

0.033

  1. Continuous variables of normal distribution were expressed as mean ± SD and compared by the Student’s t test. Non-normal distribution variables were expressed as and median (interquartile range 25–75%) and compared by the Mann-Whitney U test. Categorical variables were expressed as percentages and compared by the Chi-square test.
  2. SRC, simple renal cysts; BMI, body mass index; DD, duration of diabetes; SUA, serum uric acid; SCr, serum creatinine; eGFR, estimated glomerular filtration rate; ALT, alanine aminotransferase; AST, aspartate aminotransferase; γ-GT, γ-glutamyl transferase; TC, total cholesterol; TG, total triglycerides; HDL-C, high-density lipoprotein cholesterol; LDL-C, low-density lipoprotein cholesterol; FPG, fasting plasma glucose; HbA1c, glycosylated hemoglobin; 24-h UUA, 24-hour urine uric acid; 24-h UCr, 24-hour urine creatinine; 24-h UGLU, 24-hour urine glucose; FEUA, fraction excretion of uric acid.