Figure 4
From: A microRNA signature of response to erlotinib is descriptive of TGFβ behaviour in NSCLC

Time of TGFβ treatment reflects changes in endogenous miRNA gene expression. Changes in endogenous gene expression were analysed using a five-way ANOVA considering the variables: TGFβ treatment, SB-431542 treatment, time point, expression as internally normalized Ct values, and cell line, along with all interaction terms. (a) Data presented here is aggregated by averaging over treatments in order to capture overarching trends in miRNA and cell line patterns at multiple time points. Fine-scale trends were broken down by individual treatments as presented in Supplemental Figure 4. (b) Comparison of the significance of endogenous expression changes between time points samples and by individual miRNA genes in each cell line.