Figure 2
From: Systemic blockade of P2X7 receptor protects against sepsis-induced intestinal barrier disruption
The effects of a P2X7R blockade on intestinal injuries. Intestinal tissues were obtained 48 hours after sepsis induction to evaluate the severity of inflammation. Representative H&E-stained intestinal sections in the BzATP-treated (A), control (B), A740003-treated (C), and sham (D) groups. The histological scores and macroscopic scores are shown in (E,F). (G) The intestinal samples of animals from each group were homogenized and protein was extracted for MPO activity analysis. N = 6 mice per group. The data are expressed as the means ± SD. *p < 0.05, **p < 0.01 and ***p < 0.001 when compared among the different groups.
