Figure 8 | Scientific Reports

Figure 8

From: Systemic blockade of P2X7 receptor protects against sepsis-induced intestinal barrier disruption

Figure 8

The effects of a P2X7R blockade on the ERK and NF-κB pathways. The protein levels of p-ERK 1/2 and ERK 1/2 (A), NF-κB p-p65 and p65 (B), and p-IKK and p-IκB (C) in intestinal mucosa were measured by WB at 48 hours after CLP. N = 6 mice per group. The results of WB analysis are combined data from three densitometric scans (means ± SD). *p < 0.05, **p < 0.01 and ***p < 0.001 when compared among the different groups.

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