Table 2 Shared TCGA/CCLE epithelial state- and mesenchymal state-associated mRNAs and their associations with distant metastasis and nodal status in the TCGA COAD cohort.

From: Pan-cancer EMT-signature identifies RBM47 down-regulation during colorectal cancer progression

Shared TCGA/CCLE epithelial state-associated mRNAs

Fold change M0/M1

Fold change N0/N+

Shared TCGA/CCLE mesenchymal state-associated mRNAs

Fold change M0/M1

Fold change N0/N+

AFTPH

1.04

1.01

LGALS1

1.35*

1.23

CDH1

1

1.04

P4HA3

1.3

1.34*

CDS1

0.89*

0.90**

UROD

0.95

1.03

EPCAM

1.02

1.05

VIM

1.41*

1.33*

ESRP1

1.02

1.02

   

ESRP2

1.04

1.00

   

FA2H

0.93

1.02

   

HOOK1

0.94

0.91*

   

LNX1

1.00

1.06

   

MAP7

1.01

0.94

   

MAPK13

1.03

1.06

   

MARVELD2

1.03

0.99

   

MARVELD3

0.88*

1.00

   

MYO5B

0.90*

0.92*

   

MYO5C

0.83**

0.85***

   

RBM47

0.84***

0.89***

   
  1. Fold change: average expression of indicated mRNAs in primary tumors from patients without distant metastases (M0) or negative nodal status (N0) divided by average expression of indicated mRNAs in primary tumors from patients with distant metastases (M1) or positive nodal status (N+). *P < 0.05; **P < 0.01; ***P < 0.001.
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