Figure 2
From: Cis-regulatory evolution in prokaryotes revealed by interspecific archaeal hybrids
Regulatory divergence between archaeal hybrids is revealed by ASE analysis. (A) Approximately equal numbers of orthologs show significant allelic bias favoring either the H. mediterranei (453, red) or H. volcanii allele (476, blue) (see Methods and Supplementary Fig. 4). RPKMs plotted in this figure are the mean of the two biological replicates after normalization. med, mediterranei; vol, volcanii. (B) Pairwise comparisons of adjacent genes within predicted operons show significantly more similar ASE than independently transcribed adjacent genes (Kruskal-Wallis rank sum test, p = 2.2 × 10−185 and 3.2 × 10−191 for replicates 1 and 2, respectively). Op, adjacent genes within predicted operons; Non-Op, adjacent genes outside of predicted operons.
