Figure 3

Detection of lineage-specific selection and differential fitness in low phosphate conditions. (A) For a set of 19 genes, the expected number with ASE with higher expression from the H. mediterranei alleles is plotted. The kinase gene set had 15/19 genes favoring the H. mediterranei alleles (red arrow), in both biological replicates. (B) H. mediterranei grows robustly in 0.1 mM phosphate, whereas H. volcanii does not. See also Supplementary Fig. 3.