Figure 1

The diagnosis effects (MDD vs. HS with the s/s genotype of 5-HTTLPR). The SPM⁴⁵ is displayed on the T1 weighted MRI. The volume of the left insula lobe was smaller in MDD patients than in HS (FWE-corrected p = 0.049, T = 4.40). The color bar represents the range of the T-value.