Table 1 Summary of RNAi phenotypes for the selected genes in lineage analysis.
Class | Gene name | Gene function | Overall phenotype | Lineage phenotype |
|---|---|---|---|---|
Chromatin structure and dynamics | cbr-lin-53 | Nucleosome remodeling factor | Embryonic lethality | Slower division |
cbr-swsn-6 | SWI/SNF nucleosome remodeling complex component | Embryonic lethality | Division symmetry breaking | |
cbr-let-418 | Predicted helicase | Embryonic lethality | Lineaging marker depletion | |
cbr-lin-40 | Histone deacetylase complex | Wildtype | Wildtype | |
cbr-isw-1 | Chromatin remodeling complex NURF | Wildtype | Division symmetry breaking | |
Posttranslational modification | cbr-smo-1 | Ubiquitin-like proteins | Embryonic lethality | Division symmetry breaking |
cbr-sip-1 | Heat shock protein | Wildtype | Wildtype |
