Table 3 Multivariate-adjusted OR and 95% CI for asymptomatic ICAS according to eGFR and proteinuria.

From: Decreased Estimated Glomerular Filtration Rate (eGFR), Not Proteinuria, Is Associated with Asymptomatic Intracranial Arterial Stenosis in Chinese General Population

 

Case (n)

Crude OR (95% Cl)

Model 1 OR (95% Cl)

Model 2 OR (95% Cl)

ICAS (n = 684)

eGFR (ml/min/1.73 m2)

 ≥90

321

1.00 (Reference)

1.00 (Reference)

1.00 (Reference)

 60–89

306

1.64 (1.39–1.94)

1.09 (0.90–1.32)

1.12 (0.92–1.36)

 45–59

38

1.98 (1.36–2.87)

1.26 (0.85–1.86)

1.23 (0.81–1.87)

 <45

19

6.77 (3.67–12.49)

3.92 (2.07–7.43)

3.29 (1.67–6.51)

 P for trend

 

<0.001

0.003

0.01

Proteinuria

 Negative

95

1.00 (Reference)

1.00 (Reference)

1.00 (Reference)

 Positive

25

1.77 (1.13–2.77)

1.54 (0.97–2.44)

1.01 (0.62–1.65)

  1. ICAS: intracranial artery stenosis; eGFR: estimated glomerular filtration rate; OR: odds ratio; CI: confidence interval. Model 1: adjusted for age and gender. Model 2: adjusted for age, gender, BMI, SBP, TC, TG, LDL cholesterol, HDL cholesterol, current smoking, current drinking, HBP, DM, dyslipidemia, education, income and physical activity.
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