Figure 6

Molecular surface representation (light grey) of PE8 and R. sphaeroides RspE (PDB 4FHZ). (A) p-NP acetate docks into the substrate-binding pocket of PE8 chain B, which is shown as a cartoon representation in red (Arg79 is shown as a stick). (B) RspE is shown as a cartoon representation in orange. The relatively closed cavity of the substrate-binding pocket caused by Arg79 in PE8 and the open cleft in RspE are indicated with black circles. Red arrows indicate the β3 loops.