Table 1 Brain areas showing significantly increased activation before and after oxaliplatin infusion.

From: Brain activity changes in a macaque model of oxaliplatin-induced neuropathic cold hypersensitivity

Area

Hemisphere

Z value

x

y

z (mm)

Intact (10 °C–37 °C)

PE/PG

Right

3.99

−18

−2

16

PN

Right

3.85

−2

0

−12

SI

Left

3.49

4

2

20

PMd

Left

3.44

4

26

16

Left

2.99

12

18

16

TEd

Right

3.43

−24

0

−6

TG

Right

3.18

−12

18

−8

Cb

Right

3.04

−8

−10

−12

Post-oxaliplatin (10 °C–37 °C) > Intact (10 °C–37 °C)

SII/Ins

Right

3.64

−16

20

2

Left

3.10

14

16

2

Cb

Left

3.04

8

−8

−8

  1. Z -value of the peak voxels are indicated. The locations are indicated with the positions along the x (ipsi-contralateral), y (rostro-caudal) and z (dorso-ventral) axes of the Horsley-Clarke stereotaxic coordinates. Cb, cerebellum; PMd, dorsal premortor cortex; TEd, dorsal inferotemporal cortex; Ins, Insular cortex; PE/PG, PE/PG of the inferior parietal cortex; PN, pontine nuclei; SI, primary somatosensory cortex; SII, secondary somatosensory cortex; TG, temporal pole.