Table 1 Binding characteristics of used mAbs.

Mab	M/H	Binding	Neutralization (W/M/S)	Binding region	Binding DENV serotypes					Ref.
Mab	M/H	Binding	Neutralization (W/M/S)	Binding region	DV1	DV2	DV3	DV4	ZIKV	Ref.
4G2	M	F-CR	W	DII FL	++	++	+++	+++	+++	41
2D22	H	DV2	DV2:S ZIKV:W	DI/DII Q	−	++	−	−	−	22, 36
1M7	H	F-CR	M	DII FL	+++	++	+++	+++	+++	27
A11	H	F-CR	DV:S ZIKV:W	DI/DII/DII Q	+++	+++	+++	+++	+	38
B7	H	F-CR	DV:S ZIKV:W	DI/DII/DII Q	+++	+++	+++	+++	+	38
C8	H	F-CR	DV:S ZIKV:S	DI/DII/DII Q	+++	+++	+++	+++	++	38
C10	H	F-CR	DV:S ZIKV:S	DI/DII/DII Q	+++	+++	+++	+++	++	38

Characteristics of the mAbs used for dimer assembly. Several mouse or human (M/H) derived mAbs were used for sRecE dimer assembly, indicating their DENV and ZIKV binding potential. Flavivirus cross reactive (F-CR), weakly, medium or strong (W/M/S) neutralizing, E-domain I, II, III (DI, DII, DIII), fusion loop (FL), quaternary epitope (Q).

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