Figure 1
From: Human Cochlear Histopathology Reflects Clinical Signatures of Primary Neural Degeneration
Representative cochlear histopathology in severe primary neural degeneration compared to age-matched control. In both examples, sensory structures are normal. (a) mid-modiolar section (4X) from the cochlea of a patient with appropriate SGN numbers for age; scale bar 1 mm. The boxed area is shown magnified in b. (b) 10X magnification of the modiolus in a; scale bar 200 μm. (c) Mid-modiolar section (4X) from an age-matched patient with severe primary neural degeneration (Patient 19), showing 85% fewer total SGN cell bodies than expected for age; scale bar 1 mm. The boxed area is shown magnified in d. (d) 10X magnification of the modiolus in c; scale bar, 200 μm.
