Figure 2
From: Human Cochlear Histopathology Reflects Clinical Signatures of Primary Neural Degeneration
Patients with severe neural degeneration show abnormally low SGN counts with respect to age. SGNs quantified by cochlear segment in 51 ears from 34 patients. (a) Gray circles: published age-based mean with standard deviation and linear regression (Makary et al., 2011); black squares: patients with SGN counts greater than one standard deviation below the age-based mean; white squares: all other patients. (b) Schematic of cochlear segments, as in Makary et al., 2011. (c) Heat map of 30 ears from 23 patients exhibiting total neuronal loss (%) greater than one standard deviation below the age-based mean; each line represents a single ear.
