Table 1 Summary of clinical characteristics among patients with SGN counts greater than one standard deviation below the mean expected for age, despite a normal complement of sensory cells (n = 30 ears belonging to 23 patients).
From: Human Cochlear Histopathology Reflects Clinical Signatures of Primary Neural Degeneration
Patient | Age | Sex | Ear | Primary otologic diagnosis | Cause of death |
|---|---|---|---|---|---|
1 | 11 | F | R | Neuroaxonal dystrophy | Respiratory arrest |
L | |||||
2 | 18 | M | L | Severe neural degeneration | Craniopharyngioma |
3 | 19 | M | R | Fibrous sclerosis of middle ear | Renal failure |
L | |||||
4 | 30 | M | R | Sclerosteosis | Postoperative complications of cranial decompression |
5 | 32 | M | R | Histiocytosis | Thyroid carcinoma with metastasis |
6 | 39 | M | R | Exostosis of external auditory canal | Malignant lymphoma |
7 | 41 | F | R | Severe atrophy of cochlear nerve, etiology undetermined | Epipharyngeal carcinoma |
8 | 56 | M | R | Presbycusis | Bacterial endocarditis |
9 | 59 | F | R | Acute otitis media | Intracranial hemorrhage |
10 | 59 | M | L | Hypoplastic dysmorphic modiolus | Ruptured aortic aneurysm |
11 | 61 | M | R | Mohr-Tranebjaerg syndrome | Unknown |
L | |||||
12 | 62 | M | R | Chronic otitis media | Unknown |
L | |||||
13 | 63 | M | L | Otosclerosis | Intracranial hemorrhage |
14 | 64 | M | L | Primary neural degeneration | Chronic respiratory insufficiency |
15 | 67 | M | R | High-tone hearing loss | Acute urinary failure |
16 | 67 | M | L | Presbycusis | Hepatic failure with gastrointestinal hemorrhage |
17 | 70 | M | R | Otosclerosis | Malignant lymphoma |
L | |||||
18 | 71 | F | L | Primary neural degeneration | Intracerebral hemorrhage |
19 | 71 | M | R | Neural presbycusis | Necrotizing bronchopneumonia |
L | |||||
20 | 76 | F | R | Presbycusis | Coronary thrombosis |
21 | 78 | M | R | Presbycusis | Cardiopulmonary arrest |
L | Meniere’s, presbycusis | ||||
22 | 79 | M | R | Presbycusis | Cardiovascular accident |
23 | 99 | F | L | Presbycusis | Unknown |
