Figure 3 | Scientific Reports

Figure 3

From: Exosomes from metastatic cancer cells transfer amoeboid phenotype to non-metastatic cells and increase endothelial permeability: their emerging role in tumor heterogeneity

Figure 3

Exosomes released by metastatic cells enhance motile and invasive properties of less aggressive tumor cells. Transwell migration (A) and invasion (B) assay of SW480 cells treated with increasing doses (20 or 50 µg/ml) of SW480Exos or SW620Exos. Representative micrographs (upper panel) and quantitative data (lower panel) are reported for each assay. Ctrl (Control): SW480 cells without exosome treatment. Values reported in the graphs are the mean ± SD of 5 fields in three independent experiments. Statistical significance was calculated vs ctrl and between the same doses of SW480Exos and SW620Exos as indicated by the horizontal lines; *p ≤ 0.05, **p ≤ 0.01.

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