Figure 1

Study flowchart. Selection of participants from study A (Light grey boxes) and study B (Darker grey boxes). Hatched grey boxes: Participants from both studies. Study A was a randomized-controlled trial (rct) of the effect of different micronutrient supplementary as an adjunct to anti-tuberculosis therapy (ATT), carried out from January 2008 to June 2012 in Delhi, India. Study B: A neonatal cohort study (NCS) of BCG-vaccinated neonates randomized to active or passive surveillance for 3 years, in Palamaner Taluk, India, April 2007 to September 2010. ¹Inadequate samples or lost to follow-up. ²Ninety of 692 were either QFT/TST positive, or both, indicating M. tuberculosis (Mtb) infection. ³Criteria for possible TB: ≥1 sign and symptom for TB, and either; response to treatment/documented exposure/immunological evidence of Mtb-infection, or; X-ray consistent with TB. ⁴TB ruled out by clinical, radiological and microbiological examination.