Table 2 Gene expression and slope coefficients for each biomarker for the identified signatures.
From: Novel transcriptional signatures for sputum-independent diagnostics of tuberculosis in children
7-transcript signature | 10-transcript signature | ||||
|---|---|---|---|---|---|
Expression TB cases | Gene | Slope Coefficient* | Expression TB cases | Gene | Slope Coefficient* |
Increased | GBP5 | 0.32 | Increased | GBP5 | 0.36 |
IFITM1/3 | 0.74 | IFITM1/3 | 0.47 | ||
KIF1B | 4.26 | KIF1B | 5.28 | ||
MMP9 | 0.10 | NLRP3 | 10.14 | ||
NOD2 | 0.43 | NOD2 | 4.65 | ||
TNIP1 | 12.12 | TNIP1 | 4.90 | ||
Decreased | CD3E | −2.78 | Decreased | IFNG | −30.20 |
NLRP1 | −1.97 | ||||
TAGAP | −0.22 | ||||
TGFBR2 | −0.47 | ||||
