Figure 1

YYJD inhibits the proliferation and induces cell cycle arrest at G2/M phase of lung cancer cells. (A) The effects of YYJD and Jinfukang on 95-D, A549, BEAS-2B and 16HBE cells proliferation after 24 h treatment. (B) YYJD and Jinfukang induce cell cycle arrest at G2/M phase, and the effects of YYJD and Jinfukang on 95-D and A549 cells were analyzed by flow cytometry. (C) The effects of various concentrations of YYJD on 95-D and A549 cells viability after 24 h, 48 h and 72 h treatment. (D) The expression levels of cell cycle relevant proteins. The results are expressed with the mean ± SD for at least three independent experiments. *P < 0.05, **P < 0.01 and ***P < 0.001 compared with control group (culture medium only).