Figure 3 | Scientific Reports

Figure 3

From: Herbal formula YYJD inhibits tumor growth by inducing cell cycle arrest and senescence in lung cancer

Figure 3

YYJD induces premature senescence and the increase of IL-6 and IL-8 in lung cancer cells. (A) Senescence-associated β-galactosidase (SA-β-gal) activity. The cells after YYJD-treated show more positive cells (green color) compared with the control by SA-β-gal staining. Quantitative analysis of cellular senescence from SA-β-gal staining shows that the percentage of positive cells is markedly higher in YYJD-treated cells. (B) ELISA analysis of IL-6 and IL-8 in A549 cells. (C) qT-PCR analysis of IL-6 and IL-8 mRNA in A549 cells. Data are obtained from three independent experiments and shown as mean ± SD. *P < 0.05, **P < 0.01 and ***P < 0.001 compared with control group (culture medium only).

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