Figure 1 | Scientific Reports

Figure 1

From: Association between BRAF V600E Mutation and Ultrasound Features in Papillary Thyroid Carcinoma Patients with and without Hashimoto’s Thyroiditis

Figure 1

A 54-year-old woman with papillary thyroid carcinoma. (a) A solid, hypoechogenic, irregular and ill-defined nodule (arrows) with capsule contact and involvement (triangle) is shown on US and macrocalcifications with acoustic shadow are found in the nodule. (b) The nodule shows rich blood flow distributed internally and peripherally on color Doppler US. (c) Pathological examination confirms the diagnosis of papillary thyroid carcinoma with local invasion of thyroid capsule and Hashimoto’s thyroiditis. (haematoxylin-eosin stain; original magnification, ×40). (d) The amplification plot of BRAF shows BRAF mutation type. The purple curve, representative of the BRAF sample, is up between the two light blue reference lines. The horizontal light blue line suggests BRAF-negative, while the upward light blue curve suggests BRAF-positive.

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