Figure 3 | Scientific Reports

Figure 3

From: Controllable Microfluidic Production of Drug-Loaded PLGA Nanoparticles Using Partially Water-Miscible Mixed Solvent Microdroplets as a Precursor

Figure 3

The evolution processes of different precursor fluids. (a) Scheme of the device with locations of the position for the images (b–e); (b–e) Flow-focusing of partially water-miscible precursor (V DCM /V DMSO  = 1/10) and water, Qcon = 10000 µL/hr, Qdis = 100 µL/hr. Photos were taken at positions close to nozzle (b), 10 mm after nozzle (c), 20 mm after nozzle (d), and 30 mm after nozzle (e), along the flow direction, successively. After 30 mm, the size of the droplets is submicronic since they are not observable using an optical microscope.

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