Figure 6
From: Ssu72 attenuates autoimmune arthritis via targeting of STAT3 signaling and Th17 activation
Ssu72 overexpression exerts therapeutic effects on CIA in an in vivo model by controlling B cell responses. (A) The populations of GL-7-producing B220+CD95+ B cells in splenocytes from mice with CIA (mock or Ssu72-overexpressing) were analyzed by intracellular flow cytometry. (B) Populations of IL-10-producing CD19+CD5+CD1d+ B cells in splenocytes from mice with CIA were analyzed by intracellular flow cytometry. The data represent the mean ± SD from three independent experiments. Statistical analyses were conducted using the nonparametric Mann-Whitney U-test (**P < 0.03, ***P < 0.01, n = 6).
