Figure 5
From: Defective CFTR leads to aberrant β-catenin activation and kidney fibrosis

Development of kidney fibrosis is aggravated in deltaF508 mice. (a) CFTR mutation aggravates kidney fibrosis manifestation in deltaF508 mice compared to wild type mice after UUO procedure. Collagen I staining and F4/80 staining; (b) Quantification analysis of Collagen I staining and F4/80 staining, representing mean ± SEM from three mice. *P < 0.05, **p < 0.01, ***p < 0.001 compared with wild type mice.