Figure 1

Experimental setup and the optimization of nebulizing gas flowrate and extracted solvent flowrate of the LE-ESSI. (A) 3D view schematic representation of the LE-ESSI device. (B) Schematic diagram of LE-ESSI MSI. (C) The entry & exit delay time of the extracted analytes when liquid bridge was located into or out off of the blue ink band at different nebulizing gas flowrate and different solvent flowrate. (D) Optical images and ion images of the blue ink patterns at different nebulizing gas flowrate.