Figure 2
From: PSMA expression by microvasculature of thyroid tumors – Potential implications for PSMA theranostics
Potential imaging pitfalls associated with PSMA expression in thyroid lesions. (A) Significant heterogeneity within follicular carcinoma. Two neighboring areas with high (B) and negative (C) PSMA expression in tumor capillaries. Arrowheads indicate PSMA-negative microvessels. (D) Hashimoto’s thyroiditis with prominent PSMA immunoreactivity in lymphoid follicles (E) due to cytoplasmic staining of dendritic cells (F). Note absence of PSMA-positive endothelium. Immunohistochemistry, 100× (A,E), 400× (B,C), 20× (D), 800× (F).
