Table 1 Top-15 upregulated genes in the testes of PLAG1-deficient mice.
From: PLAG1 deficiency impairs spermatogenesis and sperm motility in mice
Gene symbol | Gene name | FDR | Log fold change | Counts per million | GO terms | ||||
|---|---|---|---|---|---|---|---|---|---|
WT | HET | KO | Molecular function | Cellular component | Biological process | ||||
Lcn9 | Lipocalin 9 | 5.62E-22 | 11.485 | 0.0 | 0.03 | 64.3 | Catalytic activity, Binding | Extracellular region | Metabolic process, Cellular process, Localization |
4933400L20Rik | RIKEN cDNA 4933400L20 gene | 5.62E-22 | 1.614 | 8.9 | 27.2 | 28 | ND | ND | ND |
Teddm1 | Transmembrane epididymal protein 1 A | 1.26E-17 | 9.823 | 0.07 | 0.1 | 54.8 | ND | Membrane | ND |
Lcn8 | Lipocalin 8 | 2.81E-16 | 10.196 | 0.07 | 0.03 | 92.8 | Catalytic activity, Binding | Extracellular region | Metabolic process, Cellular process, Localization |
9230110F15Rik | RIKEN cDNA 9230110F15 gene | 2.32E-15 | 10.761 | 0.0 | 0.0 | 22.7 | ND | ND | ND |
Ovch2 | Ovochymase 2 | 8.46E-15 | 9.763 | 0.0 | 0.03 | 11.2 | Catalytic activity | Extracellular region | Reproduction, Metabolic process |
Adam28 | A disintegrin and metallopeptidase domain 28 | 1.84E-14 | 10.465 | 0.03 | 0.03 | 45.4 | Catalytic activity, Binding | Membrane | Reproduction, Apoptotic process, Multicellular organismal process, Development process |
Gpx5 | Glutathione peroxidase 5 | 1.45E-12 | 12.180 | 0.1 | 32.2 | 499.7 | Catalytic activity, Antioxidant activity | Extracellular region, Extracellular matrix, Membrane | Immune system process, Metabolic process, Response to stimulus |
5830403L16Rik (Teddm2) | Transmembrane epididymal family member 2 | 2.89E-12 | 3.594 | 1.2 | 0.96 | 15.4 | ND | ND | ND |
Defb25 | Defensin beta 25 | 7.70E-12 | 8.565 | 0.03 | 0.07 | 15.4 | ND | Cell part, Extracellular region | Immune system process, Response to stimulus |
Gm4846 | Predicted gene 4846 | 3.65E-11 | 4.586 | 1.5 | 1.5 | 37.1 | Catalytic activity | ND | Metabolic process |
Cst11 | Cystatin 11 | 3.30E-10 | 7.700 | 0.2 | 0.7 | 46.07 | Catalytic activity, Binding, Enzyme regulator activity | Extracellular region | Metabolic process, Biological regulation |
Lcn10 | Lipocalin 10 | 5.86E-10 | 12.554 | 0.0 | 0.13 | 21.3 | Catalytic activity, Binding | Extracellular region | Metabolic process, Cellular process, Localization |
Gm3428 | Predicted gene 3428 | 6.83E-10 | 8.739 | 0.0 | 0.0 | 1.5 | ND | ND | ND |
Defb47 | Defensin beta 47 | 3.47E-09 | 7.162 | 0.2 | 0.1 | 31.1 | ND | ND | Immune system process, Metabolic process, Response to stimulus |
