Table 1 Descriptive statistics of LS and non-LS groups.
From: Common variants of T-cells contribute differently to phenotypic variation in sarcoidosis
Variable | non-LS (N = 664) | LS (N = 384) | HC (N = 2,086) | P-value | ||||
|---|---|---|---|---|---|---|---|---|
Gender (% of male) | 57.8% | 55.2% | 28.4% | — | ||||
Age, (years), mean ± SD | 43.4 ± 12.3 | 38.49 ± 9.7 | 53.4 ± 11.3 | — | ||||
BAL T-cell distribution and flow cytometry data | Mean | Median | SD | Mean | Median | SD | P -value | |
Total Cell Number | 174990.02 | 96115 | 330483.3 | 132073.1 | 95645 | 134349.5 | — | 0.345 |
Percentage of T-cells | 29.08% | 28.90% | 13.60% | 28.17% | 27.10% | 15.02% | — | 0.312 |
Count of T-cells | 52724.78 | 23638 | 118425.5 | 39164.2 | 19923 | 70875.5 | — | 0.086 |
Percentage of T-cells CD3+ | 60.14% | 68.15% | 27.88% | 65.05% | 75.00% | 26.58% | — | 0.107 |
Count of T-cells CD3+ | 19687.79 | 12424 | 25002.606 | 17918.12 | 10196.5 | 22035.19 | — | 0.428 |
Percentage of T-cells CD4+ | 77.17% | 79.90% | 13.92% | 80.59% | 84.30% | 12.67% | — | 0.006 |
Count of T-cells CD4+ | 16003.81 | 9726 | 21707.4 | 15144.81% | 8400 | 20112.89 | — | 0.648 |
Percentage of T-cells CD8+ | 18.32% | 15.80% | 12.63% | 15.14% | 11.90% | 11.44% | — | 0.005 |
Count of T-cells CD8+ | 3057.09 | 1710 | 3970.55 | 2140.82 | 1378.00 | 3111.50 | — | 0.012 |
CD4/CD8 ratio | 6.72 | 4.90 | 5.84 | 9.57 | 7.30 | 9.96 | — | 0.005 |
CD4/CD8 ratio in LS HLA-DRB1*03 carriers | — | — | — | 10.04 | 6.80 | 11.76 | — | 0.962 |
CD4/CD8 ratio in LS HLA-DRB1*03 non-carriers | — | — | — | 8.40 | 7.20 | 5.77 | — | — |
