Table 2 Characteristics of patients.

From: Evaluation and diagnostic potential of circulating extracellular vesicle-associated microRNAs in adrenocortical tumors

Sample number

Tumor type

Cohort

Sex

Age at blood taking (year)

Hormonal activity

Ki-67 (%) or mitotic index (N/10 HPF)

Weiss score

ENSAT Tumor stage

1

ACC

Screening

F

51

Cortisol

25%

9

1

2

ACC

Screening

F

62

Subclinical testosterone

5/10 HPF

7

3

3

ACC

Screening

F

46

Non-secreting

10/10 HPF

6

4

4

ACC

Screening

M

43

Non-secreting

n.d.

6

4

5

ACC

Screening

F

57

Non-secreting

20–25%

5

4

6

ACC

Screening

F

36

Cortisol

n.d.

n.d.

4

7

ACC

Validation

F

67

Cortisol

n.d.

n.d.

4

8

ACC

Validation

F

39

Subclinical cortisol

10%

7

1

9

ACC

Validation

F

57

Non-secreting

n.d.

5

4

10

ACC

Validation

M

80

Non-secreting

n.d.

9

3

11

ACC

Validation

F

56

Testosterone

n.d.

6

2

12

ACC

Validation

M

53

Non-secreting

n.d.

9

3

13

ACC

Validation

F

31

Cortisol

n.d.

6

2

14

ACC

Validation

F

58

Testosterone

2/10HPF

4

3

15

ACC

Validation

F

24

Androgens

10%

5

2

16

ACC

Validation

F

22

Subclinical cortisol and androgens

10%

3

1

17

ACC

Validation

M

62

Cortisol

30%

7

2

18

ACC

Validation

M

48

Cortisol

15%

8

3

19

ACC

Validation

F

38

Cortisol, androgens

70%

8

2

20

ACC

Validation

F

32

Non-secreting

5%

3

1

21

ACC

Validation

F

20

Non-secreting

5

3

4

22

ACC

Validation

M

51

Non-secreting

2%

 

4

23

ACA

Screening

F

64

Aldosterone

n.d.

n.d.

 

24

ACA

Screening

F

73

Non-secreting

n.d.

n.d.

 

25

ACA

Screening

F

63

Non-secreting

n.d.

n.d.

 

26

ACA

Screening

F

59

Subclinical cortisol

n.d.

n.d.

 

27

ACA

Screening

F

77

Non-secreting

n.d.

n.d.

 

28

ACA

Screening

F

61

Cortisol

n.d.

n.d.

 

29

ACA

Validation

F

38

Non-secreting

n.d.

n.d.

 

30

ACA

Validation

F

74

Non-secreting

n.d.

n.d.

 

31

ACA

Validation

F

52

Non-secreting

n.d.

n.d.

 

32

ACA

Validation

M

29

Non-secreting

n.d.

n.d.

 

33

ACA

Validation

M

71

Non-secreting

n.d.

n.d.

 

34

ACA

Validation

F

81

Non-secreting

n.d.

n.d.

 

35

ACA

Validation

M

63

Non-secreting

n.d.

n.d.

 

36

ACA

Validation

M

50

Non-secreting

n.d.

n.d.

 

37

ACA

Validation

F

50

Cortisol

n.d.

n.d.

 

38

ACA

Validation

F

69

Cortisol

n.d.

n.d.

 

39

ACA

Validation

F

46

Aldosterone

n.d.

n.d.

 

40

ACA

Validation

M

62

Cortisol

n.d.

n.d.

 

41

ACA

Validation

F

33

Cortisol

n.d.

n.d.

 

42

ACA

Validation

F

35

Non-secreting

n.d.

n.d.

 

43

ACA

Validation

F

65

Non-secreting

n.d.

n.d.

 

44

ACA

Validation

F

54

Non-secreting

n.d.

n.d.

 

45

ACA

Validation

F

66

Non-secreting

n.d.

n.d.

 

46

ACA

Validation

M

68

Non-secreting

n.d.

n.d.

 
  1. n.d.: no data, HPF: high power field, F: female, M: male.