Figure 3 | Scientific Reports

Figure 3

From: Conformational Transitions of the Pituitary Adenylate Cyclase-Activating Polypeptide Receptor, a Human Class B GPCR

Figure 3

Interactions within the 7TM. (A) A H-bond network within the 7TM. (B) Water-density cross section with the hydrophobic region of L1922.53, L2443.47, L3586.45, and V3967.53 (spheres). A penetration is suggested in G1 and G2. (C) The salt bridge E344ICL3-R185ICL1 in two different states. (D) Time evolution of nearest polar atom distance in E344ICL3-R185ICL1.

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